The Nurse Is Reviewing Medication Information with a Nursing Student

The nurse is reviewing medication information with a nursing student prior to administering an oral drug and notes that the drug has extensive first-pass effects.Which statement by the student indicates a need for further teaching about this medication?

A) "The first-pass effect means the drug may be absorbed into systemic circulation from the intestinal lumen."
B) "The first-pass effect means the drug may be changed to an inactive form and excreted."
C) "The first-pass effect means the drug may be changed to a metabolite, which may be more active than the original."
D) "The first-pass effect means the drug may be unchanged as it passes through the liver."