The muscle is an important tissue in gluconeogenesis because it can use amino acids from protein breakdown and convert them to glucose,which it then secretes into the circulation for other tissues.

Question

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Muscle tissue can break down amino acids for gluconeogenesis, but it lacks the enzyme glucose-6-phosphatase, which is necessary for the final step of glucose production. Therefore, muscles cannot secrete glucose into the circulation; this process mainly occurs in the liver (and to a lesser extent, the kidneys).

The Muscle Is an Important Tissue in Gluconeogenesis Because It