Protein aggregation is an important component of neuronal degeneration in PD, with _______, composed of _______, formed in the affected cells.

Question

Quizplus · Accepted Answer

Protein aggregation in PD is associated with Lewy bodies, which are composed of α-synuclein. Plaques and tau proteins are associated with Alzheimer's disease, and neurofibrillary tangles are also associated with Alzheimer's disease and other neurodegenerative disorders, but not with PD. Proteosomes and ubiquitin are involved in protein degradation, and while their dysfunction can contribute to neurodegeneration, they are not directly associated with protein aggregation in PD.

Protein Aggregation Is an Important Component of Neuronal Degeneration in PD