The comorbidity of HD with psychiatric symptoms/disorders is problematic for treatment of HD symptoms. Decreasing excess movement is achieved therapeutically by _______ or _______, but these treatments can lead to _______ and _______.

Question

Quizplus · Accepted Answer

Depleting vesicular DA or blocking DA receptors can help decrease excessive movement in HD, but these treatments can also lead to depression or parkinsonism. Option A is incorrect as decreasing DA synthesis would not be therapeutic in HD and blocking DA receptors would not cause mania or dysphoria. Option C is incorrect as enhancing DA reuptake is not a therapeutic approach in HD, and schizophreniform symptoms and cognitive deficits are not common side effects of the available treatments. Option D is incorrect as increasing DA synthesis or release would exacerbate the symptoms of HD, and depression or mania are not side effects of the available treatments.

The Comorbidity of HD with Psychiatric Symptoms/disorders Is Problematic for Treatment