Treatment with a potassium channel blocker such as Ampyra could improve neurotransmission in demyelinated neurons because it

Question

Quizplus · Accepted Answer

A potassium channel blocker such as Ampyra can improve neurotransmission in demyelinated neurons by allowing transmission through demyelinated fibers in the motor pathway. When nerve fibers are demyelinated, potassium ions can leak out of the nerve more easily, which can cause the neuron to become hyperpolarized and less likely to generate an action potential. By blocking potassium channels, Ampyra can reduce this leakage and increase the likelihood of successful transmission through demyelinated fibers, thereby improving neuronal signaling and functional outcomes. However, Ampyra does not enhance the generation of action potentials, hyperpolarize the membrane, or modulate release of acetylcholine at the neuromuscular junction.

Treatment with a Potassium Channel Blocker Such as Ampyra Could