The most consistent functional abnormality in the brains of individuals with schizophrenia is

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Hypofrontality refers to decreased activation in the frontal lobes of the brain, which is consistently observed in individuals with schizophrenia. This decrease in brain activity affects cognitive processes such as decision-making, attention, and working memory, which are all impaired in individuals with schizophrenia. While EEG abnormalities and eye-movement problems may also be observed in some individuals with schizophrenia, they are not as consistent as hypofrontality. Deficits in stimulus perception and cognitive processing are also observed in individuals with schizophrenia, but again, these can be a result of the hypofrontality that is consistently observed in this population.

The Most Consistent Functional Abnormality in the Brains of Individuals