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Which Findings in Rat Experiments Support Glutamate Signaling Involvement in the Positive

Question 20

Multiple Choice

Which findings in rat experiments support glutamate signaling involvement in the positive symptoms of schizophrenia?


A) Chronic AMDA antagonism causes inflammation and activation of microglia and cytokines in specific brain regions.
B) Chronic NMDA agonism causes inflammation and activation of microglia and cytokines in specific brain regions.
C) Blocking NMDA receptors in VTA results in an increase in DA release in the PFC and reduced release of DA in the nucleus accumbens.
D) Blocking NMDA receptors in VTA results in an increase in DA release in the nucleus accumbens and reduced release of DA in the PFC.

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