The most important descending pathways for modulation of spinal cord transmission of pain originate in the
A) thalamus.
B) midbrain PAG.
C) limbic system.
D) anterior cingulate cortex.

Question

Quizplus · Accepted Answer

The midbrain PAG (periaqueductal gray) is the most important descending pathway for modulation of spinal cord transmission of pain. It plays a role in both pain suppression and facilitation. The thalamus, limbic system, and anterior cingulate cortex are involved in pain perception, but do not have as direct of an impact on the modulation of spinal cord transmission of pain as the PAG.

The Most Important Descending Pathways for Modulation of Spinal Cord