Alcohol and benzodiazepines most likely show cross-tolerance and cross-dependence because they both _______ the effects of _______ at _______ receptors. A) decrease; glutamate; NMDA B) enhance; glutamate; NMDA C) decrease; GABA; GABA_A D) enhance; GABA; GABA_A

Question

Quizplus · Accepted Answer

Both alcohol and benzodiazepines enhance the effects of GABA at GABAA receptors, leading to increased inhibition and sedation. This results in cross-tolerance and cross-dependence between the two substances. Glutamate and NMDA receptors are not directly involved in the actions of alcohol and benzodiazepines.

Alcohol and Benzodiazepines Most Likely Show Cross-Tolerance and Cross-Dependence Because