Signaling between the gut 5-HT and the brain is supported by several studies, one of which showed that firing rate of vagal afferents from the gut was increased by administration
A) of a catecholamine reuptake inhibitor, but not by an SSRI.
B) of an SSRI, but not by a catecholamine reuptake inhibitor.
C) of PCPA, but not by a catecholamine reuptake inhibitor.
D) of MDMA, but not by a catecholamine reuptake inhibitor.

Question

Quizplus · Accepted Answer

The question states that signaling between the gut 5-HT and the brain is supported by several studies. It further states that the firing rate of vagal afferents from the gut was increased by administration of a certain drug. Of the options given, the only one that could plausibly increase the firing rate of vagal afferents is an SSRI. Therefore, the correct answer is B.

Signaling Between the Gut 5-HT and the Brain Is Supported