Recent research indicates that supersensitivity to a drug can be reduced by _______ of striatal D₂ receptor occupancy. A) alternating the drug of choice with placebo to allow for an increase B) complete withdrawal from the drug to allow for a reduction C) an increased dose of a drug to allow for increase D) intermittent drug dosing to allow for a reduction

Question

Quizplus · Accepted Answer

Intermittent drug dosing allows for a reduction in striatal D₂ receptor occupancy, which can reduce supersensitivity to the drug. Alternating the drug of choice with placebo may not be effective in reducing supersensitivity, and increasing the dose may exacerbate the problem. Complete withdrawal from the drug may also not be feasible or safe in all cases.

Recent Research Indicates That Supersensitivity to a Drug Can Be