When optogenetics is used to insert channelrhodopsin-2 (ChR2) in a neuron, activating this protein with light will produce an _______ of _______ ions.
A) efflux; chloride
B) influx; chloride
C) efflux; sodium
D) influx; sodium

Question

Quizplus · Accepted Answer

Channelrhodopsin-2 (ChR2) is a light-gated cation channel, meaning that it allows positive ions to flow across the cell membrane in response to light. Specifically, when activated with light, ChR2 allows an influx of sodium ions into the neuron, which depolarizes the cell and can lead to an action potential. Therefore, the correct answer is D, influx of sodium ions.

When Optogenetics Is Used to Insert Channelrhodopsin-2 (ChR2) in a Neuron