The relaxing effects of _______ on smooth muscle and the resulting dilation of the arteries are due to an increase in the second messenger _______.

Question

Quizplus · Accepted Answer

Nitric oxide (NO) causes relaxation of smooth muscle and dilation of arteries. This occurs due to an increase in the second messenger cyclic guanosine monophosphate (cGMP). Protein kinase G (PKG) is activated by cGMP and contributes to the relaxation of smooth muscle. Protein kinase A (PKA) is not involved in this process. Calcium is not a second messenger, but rather a critical ion involved in muscle contraction.

The Relaxing Effects of _______ on Smooth Muscle and the Resulting