Disability associated with sickle cell anemia is mostly due to:

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Disability associated with sickle cell anemia is mainly due to the damage caused to joint and other body organs during sickle cell crisis, which leads to permanent tissue damage. This happens because the oxygen-carrying capacity of the red blood cells is reduced, leading to diminished blood flow to specific body parts. This may cause pain, swelling, and other complications such as organ damage and stroke. Other complications that may arise due to sickle cell anemia such as infections and the need for blood transfusions can also contribute to disability, but they are not the primary cause.

Disability Associated with Sickle Cell Anemia Is Mostly Due To