A laboratory purchases a new UPLC-QQQ system that can differentiate between peaks that are 0.6 Da wide. The instrument is used to quantitate cocaine and one of the key transitions monitored yields a peak of m/z 182. What is the mass resolution of the instrument based on the peak with a nominal mass of 182 Da?

Question

Quizplus · Accepted Answer

The mass resolution of an instrument is calculated using the formula: Resolution = m/Δm, where m is the mass of the peak and Δm is the width of the peak in Da. For a peak of m/z 182 and a width of 0.6 Da, the resolution would be 182 / 0.6 = 303.33. Since none of the provided options match this calculation, the correct answer is E) none of the above.

A Laboratory Purchases a New UPLC-QQQ System That Can Differentiate