Which of the mutation types is least likely to have a phenotypic effect?

Question

Quizplus · Accepted Answer

Missense mutations involve a change in a single nucleotide that results in a different amino acid being incorporated into the protein. While this can sometimes have a significant effect on the function of the protein, it is also possible for the new amino acid to have a similar function or location in the protein and not have much impact on its overall function. Frameshift and nonsense mutations tend to have more drastic effects because they disrupt the reading frame or prematurely terminate protein synthesis, respectively. Therefore, missense mutations are least likely to have a phenotypic effect.

Which of the Mutation Types Is Least Likely to Have