The initial potentiation of a synapse does not depend on either transcription or the translation of new protein.

Question

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The initial potentiation of a synapse is mediated by the release of neurotransmitters and the activation of receptors, which leads to changes in ion conductance and intracellular signaling pathways. These changes do not require transcription or translation of new protein. However, long-term potentiation (LTP), which involves sustained changes in synaptic strength, does require synthesis of new proteins.

The Initial Potentiation of a Synapse Does Not Depend on Either