The TetTag Mouse Was an Improvement Over the Sole Use

The TetTag mouse was an improvement over the sole use of the immediate early gene Arc to tag cells because _______. (Select all that apply.)

A) immediate early genes do not respond to cell activity
B) cells in the TetTag mouse always respond to activation
C) immediate early gene markers do not persist
D) the tag established during learning can persist for many days in the TetTag mouse
E) the TetTag mouse permits temporal control over when the tag can occur.