When genetic material has been extracted from the oldest human skeletons found in the New World, their nuclear and mitochondrial genomes are most similar to which Old World people:

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Studies have found that the oldest human skeletons found in the New World, such as those from the Anzick site, have genetic material that is most similar to that of modern-day Northeast Asians. This supports the theory that the ancestors of Native Americans originated in Northeast Asia and migrated over the Bering Land Bridge into the Americas. There is no evidence that their genetic material is similar to Polynesians or South Asians.

When Genetic Material Has Been Extracted from the Oldest Human