Data from the London taxi cab driver brain study provided a clear demonstration of:

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The data from the London taxi cab driver brain study demonstrated that brain plasticity is regulated by epigenetic factors, such as changes in the environment and experience. The study showed that the hippocampus, a brain region involved in spatial navigation, was significantly larger in London taxi drivers compared to control subjects. This suggests that the extended use of spatial memory in taxi drivers leads to structural changes in the brain, demonstrating the plasticity of the brain in response to experience.

Data from the London Taxi Cab Driver Brain Study Provided