What Northern Renaissance artist was most actively engaged in the religious debates of the Reformation and the most influenced by Italian humanism?

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Albrecht Dürer was deeply engaged in the religious debates of his time, reflecting the influence of the Reformation in his work. He was also significantly influenced by Italian humanism, which he encountered during his travels to Italy, where he studied the techniques and perspectives of the Italian Renaissance. This combination of interests makes him a key figure in the Northern Renaissance who bridged the gap between the religious tumult of Northern Europe and the humanist ideals of the Italian Renaissance.

What Northern Renaissance Artist Was Most Actively Engaged in the Religious