The personality disorder associated with the greatest levels of disability is:

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Borderline personality disorder is associated with the greatest levels of disability. People with this disorder often struggle with intense and unstable emotions, impulsivity, self-harm behaviors, and difficulties in relationships. Research suggests that individuals with borderline personality disorder have high rates of psychiatric hospitalization, suicidal behavior, and significant impairments in functioning.

The Personality Disorder Associated with the Greatest Levels of Disability