An upshot of the controversy about the AZT trials in Africa was that investigators conducting a randomized clinical trial in developing countries need to consider which of the following?

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The controversy around the AZT trials highlighted the need for researchers to consider the unique circumstances of developing countries, including their approaches to individual and public health, their limited medical and financial resources, and their disproportionate burden of disease. These factors should be taken into account when designing and conducting randomized clinical trials in these settings.

An Upshot of the Controversy About the AZT Trials in Africa