The most important factor in breaking the "biological old regime" was:

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The development of ways to harness new sources of energy for production, such as fossil fuels, allowed for unprecedented economic growth and increased productivity. This led to significant changes in agriculture, manufacturing, transportation, and communication, ultimately upending the traditional ways of life that were in place before the Industrial Revolution. The Peace of Westphalia and the publication of Darwin's Origin of Species were important historical events, but they did not have the same widespread and practical impact on society as the harnessing of new sources of energy.

The Most Important Factor in Breaking the "Biological Old Regime