The largest Jewish ghetto created in Nazi-occupied Europe was in the city of:

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The largest Jewish ghetto created in Nazi-occupied Europe was in the city of Warsaw, Poland. At its peak, the Warsaw Ghetto held around 400,000 Jews who were confined to an area of only 1.3 square miles. The conditions in the ghetto were horrendous, with starvation, disease, and overcrowding leading to the deaths of tens of thousands of people. The ghetto was ultimately liquidated by the Nazis, with most of its inhabitants sent to concentration camps or killed on the spot.

The Largest Jewish Ghetto Created in Nazi-Occupied Europe Was in the City