Which of following is not an epigenetic change, broadly defined?

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Epigenetic changes refer to modifications that affect gene expression without changing the underlying DNA sequence. Methylation and acetylation are both examples of epigenetic changes. Suppression of an X chromosome in an XX person is also an example of an epigenetic change (called X chromosome inactivation). However, a single nucleotide change in a gene would be a genetic mutation, not an epigenetic change.

Which of Following Is Not an Epigenetic Change, Broadly Defined