Clinical trials may compare new and established medications, or medication vs. placebo. Drug trials that involve the use of placebos are:

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Placebos are necessary in drug trials to determine the effectiveness of a drug by comparing it to a control group who receives a placebo. This helps to ensure that any observed effects are due to the drug being tested and not simply due to the placebo effect. While drug trials may compare new and established medications, the use of placebos is an important aspect of determining the safety and efficacy of a new medication.

Clinical Trials May Compare New and Established Medications, or Medication