Postsynaptic membranes at GABAᴀ synapses become ________ when GABA binds to its receptors.

Question

Quizplus · Accepted Answer

GABAᴀ receptors are ionotropic receptors, which means that their activation causes the opening of chloride ion channels in the postsynaptic membrane. When chloride ions flow into the cell, the electrical potential of the cell becomes more negative, resulting in hyperpolarization. This makes it less likely that the neuron will fire an action potential, leading to inhibition of neuronal activity.

Postsynaptic Membranes at GABAᴀ Synapses Become ________ When GABA Binds