The monoamine hypothesis assumes that depression is a consequence of

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The monoamine hypothesis proposes that depression is caused by a deficiency of monoamine neurotransmitters, such as serotonin, norepinephrine, and dopamine, in the brain. However, this hypothesis has been revised in recent years to include the possibility that other factors, such as neurotrophic factors, may also be involved. One of these factors is the reduced production of growth factors by monoamine neurons, which can lead to neuronal degeneration and contribute to depression.

The Monoamine Hypothesis Assumes That Depression Is a Consequence of