Patients who have had untreated bipolar disorder for a long time are more likely to

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Patients with untreated bipolar disorder are at risk for neural degeneration and enlarged ventricles due to the chronic stress on the brain from the alternating periods of mania and depression. While medication can still be effective in treating bipolar disorder, it may not be as effective in individuals who have had the disorder for a long time and have experienced damage to their neural structures. Rapid-cycling symptoms can occur in bipolar disorder, but it is not necessarily more common in those with untreated bipolar disorder.

Patients Who Have Had Untreated Bipolar Disorder for a Long