Due to Spanish influences, Mesoamerica as a whole lost __________ percent of the indigenous population between A. D. 1520 and 1680.

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Due to the introduction of European diseases and warfare, it is estimated that Mesoamerica lost approximately 85 to 95 percent of its indigenous population between A. D. 1520 and 1680. This demographic catastrophe had a devastating impact on the social, political, and economic structure of the region.

Due to Spanish Influences, Mesoamerica as a Whole Lost __________