Megaloblastic anemia is a reduction in the blood's capacity to carry oxygen that is characterized by abnormally large immature and mature red blood cells.

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Megaloblastic anemia is caused by a deficiency of vitamin B12 or folate, which leads to abnormal cell division in the bone marrow resulting in the production of abnormally large and immature red blood cells (megaloblasts) that cannot mature properly and function effectively in carrying oxygen. This leads to a decrease in the number of mature red blood cells and a decrease in the blood's capacity to carry oxygen.

Megaloblastic Anemia Is a Reduction in the Blood's Capacity to Carry