High circulating levels of leptin activate the _______ satiety neurons and simultaneously inhibit the _______ hunger neurons.
A) orexin; ghrelin
B) ghrelin; orexin
C) NPY; POMC
D) POMC; NPY

Question

Quizplus · Accepted Answer

Leptin is a hormone that is secreted by adipose tissue and acts on hypothalamic neurons to regulate appetite and energy expenditure. High levels of leptin activate POMC (pro-opiomelanocortin) neurons in the arcuate nucleus of the hypothalamus, which are associated with satiety, and simultaneously inhibit NPY (neuropeptide Y) neurons, which are associated with hunger. Therefore, choice D is the correct answer.

High Circulating Levels of Leptin Activate the _______ Satiety Neurons