Adenosine regulates synaptic activity through its actions on
A) postsynaptic receptors.
B) neurotransmitter reuptake.
C) synaptic enzymes.
D) presynaptic autoreceptors.

Question

Quizplus · Accepted Answer

Adenosine regulates synaptic activity through its actions on presynaptic autoreceptors. These autoreceptors are located on the presynaptic neuron and can inhibit the release of neurotransmitters in response to high levels of adenosine. Thus, adenosine can act as a negative feedback mechanism to regulate excessive neuronal activity.

Adenosine Regulates Synaptic Activity Through Its Actions on