Horseradish peroxidase (HRP) is a molecule that can be taken up by axon terminals and then carried back to the cell body for visualization of the neuron. Dysfunction in which cellular process would prevent cell labeling by HRP?
A) Anterograde transport
B) Retrograde transport
C) Dendritic transport
D) In situ hybridization

Question

Quizplus · Accepted Answer

HRP relies on retrograde transport to travel from the axon terminals to the cell body, so dysfunction in retrograde transport would prevent successful cell labeling. Anterograde transport, dendritic transport, and in situ hybridization are not directly involved in the uptake and transport of HRP.

Horseradish Peroxidase (HRP) Is a Molecule That Can Be Taken