The inactivation gate
A) quickly opens and closes after depolarization.
B) is coupled to the movement of the activation gate, but is much slower.
C) depends on a change of +100 mV from rest to be signaled to close.
D) depends on a loss of Na⁺ permeability to be triggered.
E) depends on a loss of K⁺ permeability to be triggered.

Question

Quizplus · Accepted Answer

The inactivation gate is coupled to the movement of the activation gate but is much slower. After depolarization, the activation gate opens rapidly, allowing Na+ ions to enter the cell. The inactivation gate then slowly closes, blocking further Na+ ion flow. This process is critical in the generation and propagation of action potentials.

The Inactivation Gate