The cause of skeletal muscle fatigue during extended submaximal exercise is primarily a(n)
A) depletion of glycogen stores.
B) depletion of creatine stores.
C) increased inorganic phosphate (Pi) concentration.
D) depletion of K⁺ stores.

Question

Quizplus · Accepted Answer

The primary cause of skeletal muscle fatigue during extended submaximal exercise is the depletion of glycogen stores. Glycogen is a critical energy source for muscle contractions, and its depletion leads to reduced energy availability, contributing to fatigue.

The Cause of Skeletal Muscle Fatigue During Extended Submaximal Exercise