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Mike Has Classical Hemophilia, a Clotting Disorder, but His Case

Question 103

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Mike has classical hemophilia, a clotting disorder, but his case is considered "mild." Contrary to popular belief, Mike doesn't usually have problematic bleeding episodes related to cutting himself; a more severe problem for him would be brought on by a sprained ankle or by having a full body impact, like falling off a horse and landing hard on the ground, injuries considered "closed." With what you have learned about blood coagulation, can you explain how this could be so? Assuming Mike is lacking factor VIII, which pathways does he depend on?

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Only the intrinsic pathway requires fact...

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