In type 2 diabetes, insulin levels are frequently normal, yet the target cells are less sensitive to the effects of insulin.This suggests that the target cells

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The fact that insulin levels are normal indicates that the problem does not lie with insulin production, but rather with the response of target cells. This suggests that there may be a defect in the signal transduction pathway, which is responsible for transmitting the signal from insulin to the cell's interior where glucose uptake occurs. Impermeability to insulin (choice A) would result in low insulin levels rather than normal levels, while choices C and D are not supported by the information given.

In Type 2 Diabetes, Insulin Levels Are Frequently Normal, Yet