Which of the following drugs would be an effective means for lowering plasma cholesterol levels?
A) a drug that binds to bile acids and prevents them from being reabsorbed
B) a drug that stimulates intestinal cholesterol transport
C) a drug that stimulates the enzyme HMG coA reductase
D) a drug that adds plant sterols and stanols to the diet
E) a drug that binds to bile acids and prevents them from being reabsorbed or a drug that adds plant sterols and stanols to the diet

Question

Quizplus · Accepted Answer

Both drugs described in option E could effectively lower plasma cholesterol levels. A drug that binds to bile acids prevents their reabsorption, which prompts the liver to utilize more cholesterol to produce new bile acids, thereby reducing the cholesterol pool in the body. Plant sterols and stanols are structurally alike to cholesterol and could block cholesterol uptake in the intestines, further reducing cholesterol levels. Option A alone may be insufficient in lowering plasma cholesterol levels, while option B would only raise cholesterol levels. Option C describes a drug that activates cholesterol synthesis and would raise plasma cholesterol levels.

Which of the Following Drugs Would Be an Effective Means