The equivalent of an American cabinet Secretary in the EU is called a Director General.

Name: The equivalent of an American cabinet Secretary in the EU is called a Director General.
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In the European Union, the term "Director-General" is used for the head of departments or directorates-general, which is somewhat equivalent to the role of a cabinet secretary in the United States, overseeing specific areas of administration or policy.

The Equivalent of an American Cabinet Secretary in the EU