During the first month to 24 months of age, the liver of the neonate is immature. While the liver is immature, medications metabolized by the liver have:

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Medications metabolized by the liver have a longer half-life in neonates due to the immaturity of their liver. This immaturity results in reduced metabolic activity, leading to slower processing of drugs.

During the First Month to 24 Months of Age, the Liver