Why Does the Nurse Need to Read the Package Insert

Why does the nurse need to read the package insert to see if a vaccine has been properly stored before administering the vaccine?

A) Improper storage will frequently cause the vaccine to be more virulent.
B) An improperly stored vaccine can clog the needle, leading to an infiltration.
C) Improper storage or handling can result in a decrease in vaccine potency and ineffective immunization.
D) The vaccine may be too hot or too cold to inject into the muscle or subcutaneous areas.