Explain what chronic traumatic encephalopathy (CTE) is:

Question

Quizplus · Accepted Answer

The Answer is Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative brain disease that is believed to be caused by repeated head traumas, such as concussions or subconcussive hits. It has been most commonly identified in athletes who participate in contact sports, such as football, boxing, hockey, rugby, and soccer, as well as military veterans who have been exposed to blast injuries.

CTE is characterized by the abnormal accumulation of tau protein in the brain, which can disrupt normal brain function and lead to a variety of symptoms. These symptoms can include cognitive impairment, memory loss, confusion, impaired judgment, impulse control problems, aggression, depression, anxiety, suicidality, Parkinsonism, and eventually progressive dementia.

The disease can only be definitively diagnosed posthumously through a neuropathological examination of the brain tissue. During such an examination, pathologists look for the specific pattern of tau protein distribution that is unique to CTE.

As of my knowledge cutoff in 2023, there is no cure for CTE, and the treatment is primarily supportive and symptomatic. Efforts to prevent CTE focus on reducing head impacts, improving sports safety protocols, and developing better protective equipment. Research is ongoing to better understand the disease, its risk factors, and potential therapies.

Explain What Chronic Traumatic Encephalopathy (CTE) Is