The Client Is Prescribed Collagenase (Xiaflex) for Dupuytren's Contracture

The client is prescribed collagenase (Xiaflex) for Dupuytren's contracture. When developing this client's care plan, which statement by the patient would concern the nurse?
Select all that apply.

A) "I do not like the way my hand looks."
B) "I am so tired all the time."
C) "I'm surprised my hand is not painful at times."
D) "I feel confident in my balance and walking."
E) "One of my hands is swollen at times."