In the absence of his tone proteins in prokaryotes, the an ioinic charges of each inter nucleotide phosphate in DNA is neutralized by

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In prokaryotes, the ionic charges of each internucleotide phosphate in DNA are neutralized by polyamines. Polyamines are organic compounds having two or more primary amino groups - such as putrescine, spermidine, and spermine - that bind to the negatively charged phosphate groups of the DNA, stabilizing its structure.

In the Absence of His Tone Proteins in Prokaryotes, the an Ioinic