Which of the following may be used as an antidote to benzodiazepine overdose?
I. Nalmefene
II. Physostigmine
III. Protamine
IV. Flumazenil
A)I only
B)II only
C)I, II and III only
D)IV only

Question

Quizplus · Accepted Answer

Flumazenil is used as an antidote to benzodiazepines and acts as a competitive inhibitor at the GABA receptors. Nalmefene is a competitive antagonist at opioid receptors and is used in alcoholism treatment. Physostigmine is a classic acetylcholinesterase inhibitor and is used as an antidote for anticholinergics. Protamine is an anti-coagulant and complexes with heparin and neutralizes the anti-coagulative properties of both agents.

Which of the Following May Be Used as an Antidote