What is the most common and most serious adverse effect of sulindac (Clinoril)?
I. GI bleeding
II. Hyperkalemia
III. Hyponatremia

Question

Quizplus · Accepted Answer

The most common and serious side effects of sulindac, a COX-1 enzyme inhibitor, are undetected GI bleeds and hyperkalemia (high serum potassium), which can lead to arrhythmias. Hyponatremia (low serum sodium) is not a known side effect of sulindac.

What Is the Most Common and Most Serious Adverse Effect