A patient diagnosed with PCOS (polycystic ovarian syndrome) is prescribed spironolactone along with a combined estrogen-progestin. What would you tell her about the serious possible side effects of the spironolactone?

Question

Quizplus · Accepted Answer

Spironolactone, an aldosterone inhibitor and therefore a diuretic (K+ sparing), has been associated with GI bleeds, breast cancer, metaolic acidosis and hyperkalemia. The other side effects listed are primarily associated with the use of the combined estrogen-progestin.

A Patient Diagnosed with PCOS (Polycystic Ovarian Syndrome) Is Prescribed