How do each of these compounds affect the function of ATCase?
A) ATP inhibits and CTP activates
B) ATP activates and CTP inhibits
C) Both ATP and CTP inhibit
D) Both ATP and CTP activate
E) none of these is true

Question

Quizplus · Accepted Answer

ATP is an allosteric activator of ATCase, promoting the synthesis of pyrimidine nucleotides when energy and purine nucleotides are abundant. CTP, a pyrimidine nucleotide, acts as an allosteric inhibitor, reducing ATCase activity when pyrimidine nucleotides are abundant, thus providing a feedback inhibition mechanism.

How Do Each of These Compounds Affect the Function of ATCase